HCSGD entry for MNAT1

1. General information

Official gene symbolMNAT1
Entrez ID4331
Gene full namemenage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)
Other gene symbolsCAP35 MAT1 RNF66 TFB3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000079Regulation of cyclin-dependent protein serine/threonine kinase activityTASbiological_process
GO:0000082G1/S transition of mitotic cell cycleIEA TASbiological_process
GO:0000086G2/M transition of mitotic cell cycleTASbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0000718Nucleotide-excision repair, DNA damage removalTASbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005675Holo TFIIH complexIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006200ATP catabolic processIDAbiological_process
GO:0006281DNA repairTASbiological_process
GO:0006283Transcription-coupled nucleotide-excision repairTASbiological_process
GO:0006289Nucleotide-excision repairTASbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0006357Regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0006360Transcription from RNA polymerase I promoterTASbiological_process
GO:0006361Transcription initiation from RNA polymerase I promoterTASbiological_process
GO:0006362Transcription elongation from RNA polymerase I promoterTASbiological_process
GO:0006363Termination of RNA polymerase I transcriptionTASbiological_process
GO:0006366Transcription from RNA polymerase II promoterIDA TASbiological_process
GO:0006367Transcription initiation from RNA polymerase II promoterTASbiological_process
GO:0006368Transcription elongation from RNA polymerase II promoterTASbiological_process
GO:00063707-methylguanosine mRNA cappingTASbiological_process
GO:0006461Protein complex assemblyTASbiological_process
GO:0006468Protein phosphorylationIDAbiological_process
GO:0007049Cell cycleIEAbiological_process
GO:0007512Adult heart developmentIEAbiological_process
GO:0008094DNA-dependent ATPase activityIDAmolecular_function
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0008283Cell proliferationTASbiological_process
GO:0008353RNA polymerase II carboxy-terminal domain kinase activityIDAmolecular_function
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0016310PhosphorylationIDAbiological_process
GO:0021591Ventricular system developmentIEAbiological_process
GO:0043066Negative regulation of apoptotic processIEAbiological_process
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDA IMPbiological_process
GO:0047485Protein N-terminus bindingIPImolecular_function
GO:0048661Positive regulation of smooth muscle cell proliferationIEAbiological_process
GO:0050434Positive regulation of viral transcriptionTASbiological_process
GO:0051592Response to calcium ionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.23809201020.28203510500.92394579091.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2140656731
GSE13712_SHEARDown-0.0774540870
GSE13712_STATICUp0.0441427422
GSE19018Up0.2483259333
GSE19899_A1Down-0.1637846140
GSE19899_A2Down-0.4698391548
PubMed_21979375_A1Up0.0782603792
PubMed_21979375_A2Down-0.1490094192
GSE35957Down-0.2434287749
GSE36640Down-0.4501279180
GSE54402Up0.1120580634
GSE9593Down-0.1955999157
GSE43922Down-0.1216181649
GSE24585Up0.2294817049
GSE37065Up0.0373779501
GSE28863_A1Up0.2693661306
GSE28863_A2Up0.5115529484
GSE28863_A3Down-0.4225570020
GSE28863_A4Up0.4397329547
GSE48662Down-0.0498396661

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029383MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.