HCSGD entry for MMP19

1. General information

Official gene symbolMMP19
Entrez ID4327
Gene full namematrix metallopeptidase 19
Other gene symbolsMMP18 RASI-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001525AngiogenesisIEAbiological_process
GO:0001541Ovarian follicle developmentIEAbiological_process
GO:0001542Ovulation from ovarian follicleIEAbiological_process
GO:0001554LuteolysisIEAbiological_process
GO:0004222Metalloendopeptidase activityIEAmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005578Proteinaceous extracellular matrixNAScellular_component
GO:0006508ProteolysisIEA NASbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0009725Response to hormoneIEAbiological_process
GO:0022617Extracellular matrix disassemblyTASbiological_process
GO:0030154Cell differentiationIEAbiological_process
GO:0030198Extracellular matrix organizationTASbiological_process
GO:0030574Collagen catabolic processTASbiological_process
GO:0031012Extracellular matrixIEAcellular_component
GO:0051591Response to cAMPIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.11901109380.39761186510.70708706841.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0106987178
GSE13712_SHEARUp0.4227640152
GSE13712_STATICUp0.6708144448
GSE19018Up0.4683687892
GSE19899_A1Down-0.2499033363
GSE19899_A2Up0.0368159702
PubMed_21979375_A1Up0.3437116505
PubMed_21979375_A2Down-0.3815552158
GSE35957Up0.0200037390
GSE36640Up0.6664762620
GSE54402Up0.4909039835
GSE9593Up0.0651310212
GSE43922Down-0.7744436266
GSE24585Up0.1187124437
GSE37065Up0.1726578151
GSE28863_A1Up0.0181444808
GSE28863_A2Down-0.4312831649
GSE28863_A3Down-0.5363615600
GSE28863_A4Up0.0063544527
GSE48662Up0.2763267101

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

MarimastatDB00786 APRD00559

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT023166MicroarrayFunctional MTI (Weak)18668037
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.