HCSGD entry for ASGR1

1. General information

Official gene symbolASGR1
Entrez ID432
Gene full nameasialoglycoprotein receptor 1
Other gene symbolsASGPR ASGPR1 CLEC4H1 HL-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004873Asialoglycoprotein receptor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006898Receptor-mediated endocytosisTASbiological_process
GO:0030246Carbohydrate bindingIEAmolecular_function
GO:0031668Cellular response to extracellular stimulusIEAbiological_process
GO:0042803Protein homodimerization activityIEAmolecular_function
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.38666635010.37137108770.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0188503431
GSE13712_SHEARDown-1.4375766792
GSE13712_STATICDown-1.1955595498
GSE19018Down-0.1094810446
GSE19899_A1Down-0.0396876976
GSE19899_A2Up0.4102402422
PubMed_21979375_A1Up0.1042533732
PubMed_21979375_A2Up0.2201228619
GSE35957Up0.0201886541
GSE36640Up0.2176227665
GSE54402Up0.1457800652
GSE9593Down-0.0000162843
GSE43922Up0.0348162981
GSE24585Up0.1221589552
GSE37065Down-0.1245006781
GSE28863_A1Up0.0148991701
GSE28863_A2Up0.0700663448
GSE28863_A3Up0.5757583912
GSE28863_A4Up0.1291453250
GSE48662Down-0.1179551481

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018208MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.