HCSGD entry for ASTL
1. General information
Official gene symbol | ASTL |
---|---|
Entrez ID | 431705 |
Gene full name | astacin-like metallo-endopeptidase (M12 family) |
Other gene symbols | |
Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network

This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
---|---|---|---|
GO:0004222 | Metalloendopeptidase activity | IDA | molecular_function |
GO:0005737 | Cytoplasm | ISS | cellular_component |
GO:0005886 | Plasma membrane | ISS | cellular_component |
GO:0006508 | Proteolysis | IDA | biological_process |
GO:0007155 | Cell adhesion | ISS | biological_process |
GO:0008233 | Peptidase activity | IDA | molecular_function |
GO:0008270 | Zinc ion binding | IEA | molecular_function |
GO:0009566 | Fertilization | ISS | biological_process |
GO:0010954 | Positive regulation of protein processing | ISS | biological_process |
GO:0030133 | Transport vesicle | IEA | cellular_component |
GO:0060468 | Prevention of polyspermy | ISS | biological_process |
GO:0060473 | Cortical granule | ISS | cellular_component |
GO:0070001 | Aspartic-type peptidase activity | ISS | molecular_function |
GO:0070002 | Glutamic-type peptidase activity | ISS | molecular_function |
GO:2000360 | Negative regulation of binding of sperm to zona pellucida | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
p-value up | p-value down | FDR up | FDR down |
---|---|---|---|
0.4890717222 | 0.9535706812 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
Data source | Up or down | Log fold change |
---|---|---|
GSE11954 | - | - |
GSE13712_SHEAR | - | - |
GSE13712_STATIC | - | - |
GSE19018 | - | - |
GSE19899_A1 | - | - |
GSE19899_A2 | - | - |
PubMed_21979375_A1 | - | - |
PubMed_21979375_A2 | - | - |
GSE35957 | - | - |
GSE36640 | - | - |
GSE54402 | - | - |
GSE9593 | - | - |
GSE43922 | Up | 0.1035142129 |
GSE24585 | Down | -0.0233735360 |
GSE37065 | Down | -0.0634798462 |
GSE28863_A1 | Up | 0.0427941113 |
GSE28863_A2 | Up | 0.2219359898 |
GSE28863_A3 | Up | 0.3423684527 |
GSE28863_A4 | Down | -0.0505176704 |
GSE48662 | Up | 0.0580779647 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
---|---|---|---|---|---|
hsa-miR-1226-3p | MIMAT0005577 | MIRT036503 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord