HCSGD entry for MLLT4
1. General information
| Official gene symbol | MLLT4 |
|---|---|
| Entrez ID | 4301 |
| Gene full name | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| Other gene symbols | AF6 RP3-431P23.3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0005911 | Cell-cell junction | TAS | cellular_component |
| GO:0005913 | Cell-cell adherens junction | IEA | cellular_component |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0007165 | Signal transduction | IEA | biological_process |
| GO:0007267 | Cell-cell signaling | TAS | biological_process |
| GO:0008022 | Protein C-terminus binding | TAS | molecular_function |
| GO:0030054 | Cell junction | IDA | cellular_component |
| GO:0034329 | Cell junction assembly | TAS | biological_process |
| GO:0034332 | Adherens junction organization | TAS | biological_process |
| GO:0045177 | Apical part of cell | IEA | cellular_component |
| GO:0045216 | Cell-cell junction organization | TAS | biological_process |
| GO:0050839 | Cell adhesion molecule binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1516510163 | 0.9559386497 | 0.7773298871 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0370699648 |
| GSE13712_SHEAR | Up | 0.0012807674 |
| GSE13712_STATIC | Down | -0.0329409205 |
| GSE19018 | Up | 0.0760121990 |
| GSE19899_A1 | Up | 0.0707974662 |
| GSE19899_A2 | Down | -0.0460921639 |
| PubMed_21979375_A1 | Up | 0.5325599083 |
| PubMed_21979375_A2 | Up | 0.0149682531 |
| GSE35957 | Up | 0.0076235086 |
| GSE36640 | Down | -0.4843640315 |
| GSE54402 | Up | 0.2808889583 |
| GSE9593 | Up | 0.0534792147 |
| GSE43922 | Up | 0.3045439975 |
| GSE24585 | Up | 0.1465229543 |
| GSE37065 | Up | 0.3274367219 |
| GSE28863_A1 | Up | 0.3109397117 |
| GSE28863_A2 | Up | 0.4646286660 |
| GSE28863_A3 | Up | 0.2597819219 |
| GSE28863_A4 | Up | 0.0020000781 |
| GSE48662 | Up | 0.0434790731 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| (5R)-2-SULFANYL-5-[4-(TRIFLUOROMETHYL)BENZYL]-1,3-THIAZOL-4-ONE | DB08574 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018175 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022793 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-346 | MIMAT0000773 | MIRT042714 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046504 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049217 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
