HCSGD entry for MLLT3
1. General information
| Official gene symbol | MLLT3 |
|---|---|
| Entrez ID | 4300 |
| Gene full name | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 |
| Other gene symbols | AF9 YEATS3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0007379 | Segment specification | IEA | biological_process |
| GO:0009952 | Anterior/posterior pattern specification | IEA | biological_process |
| GO:0090090 | Negative regulation of canonical Wnt signaling pathway | IDA IGI | biological_process |
| GO:2000096 | Positive regulation of Wnt signaling pathway, planar cell polarity pathway | IGI | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9491364728 | 0.0085572813 | 0.9999902473 | 0.1849068627 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2780122330 |
| GSE13712_SHEAR | Down | -0.8086450638 |
| GSE13712_STATIC | Down | -0.5441771453 |
| GSE19018 | Up | 0.5964289184 |
| GSE19899_A1 | Down | -0.1952967203 |
| GSE19899_A2 | Down | -1.1558991657 |
| PubMed_21979375_A1 | Down | -1.0308571950 |
| PubMed_21979375_A2 | Down | -0.7630813439 |
| GSE35957 | Up | 0.1953792963 |
| GSE36640 | Down | -0.2570243461 |
| GSE54402 | Down | -0.6940132024 |
| GSE9593 | Up | 0.3290089756 |
| GSE43922 | Down | -0.5223954325 |
| GSE24585 | Down | -0.4264135800 |
| GSE37065 | Up | 0.3325766456 |
| GSE28863_A1 | Up | 0.0908686249 |
| GSE28863_A2 | Down | -0.4391912010 |
| GSE28863_A3 | Down | -0.0090209315 |
| GSE28863_A4 | Down | -0.0989402797 |
| GSE48662 | Up | 0.0730585385 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022911 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
