HCSGD entry for AFF1
1. General information
| Official gene symbol | AFF1 |
|---|---|
| Entrez ID | 4299 |
| Gene full name | AF4/FMR2 family, member 1 |
| Other gene symbols | AF4 MLLT2 PBM1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0164705862 | 0.9872469815 | 0.3159262200 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0100163906 |
| GSE13712_SHEAR | Up | 0.1880746882 |
| GSE13712_STATIC | Down | -0.0276073589 |
| GSE19018 | Up | 0.2421714382 |
| GSE19899_A1 | Up | 0.2484309960 |
| GSE19899_A2 | Up | 0.3487792803 |
| PubMed_21979375_A1 | Up | 0.9046184125 |
| PubMed_21979375_A2 | Up | 0.4388459033 |
| GSE35957 | Up | 0.2078427356 |
| GSE36640 | Up | 1.2405616585 |
| GSE54402 | Up | 0.5004710451 |
| GSE9593 | Up | 0.4032789616 |
| GSE43922 | Up | 0.2897160009 |
| GSE24585 | Up | 0.2787080351 |
| GSE37065 | Up | 0.0927385112 |
| GSE28863_A1 | Up | 0.4104532196 |
| GSE28863_A2 | Up | 0.4275792893 |
| GSE28863_A3 | Down | -0.0624485189 |
| GSE28863_A4 | Down | -0.4027685512 |
| GSE48662 | Down | -0.0593426614 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-877-5p | MIMAT0004949 | MIRT037336 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039920 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
