HCSGD entry for MLLT1
1. General information
| Official gene symbol | MLLT1 |
|---|---|
| Entrez ID | 4298 |
| Gene full name | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 |
| Other gene symbols | ENL LTG19 YEATS1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006469 | Negative regulation of protein kinase activity | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8505568557 | 0.2171596444 | 0.9999902473 | 0.8973838770 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1709325628 |
| GSE13712_SHEAR | Down | -0.4374707000 |
| GSE13712_STATIC | Down | -0.1625809334 |
| GSE19018 | Down | -0.0156215773 |
| GSE19899_A1 | Down | -0.3422362284 |
| GSE19899_A2 | Up | 0.0554593508 |
| PubMed_21979375_A1 | Down | -0.0968672512 |
| PubMed_21979375_A2 | Down | -0.0451086190 |
| GSE35957 | Down | -0.1787610622 |
| GSE36640 | Down | -0.1615228459 |
| GSE54402 | Up | 0.1112366340 |
| GSE9593 | Down | -0.3625332565 |
| GSE43922 | Down | -0.0217440148 |
| GSE24585 | Down | -0.1722965353 |
| GSE37065 | Down | -0.0776436644 |
| GSE28863_A1 | Up | 0.2545402021 |
| GSE28863_A2 | Up | 0.0592496810 |
| GSE28863_A3 | Up | 0.3978798657 |
| GSE28863_A4 | Up | 0.0338813297 |
| GSE48662 | Up | 0.2440897644 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT001442 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT001617 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-484 | MIMAT0002174 | MIRT041863 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
