HCSGD entry for MKLN1
1. General information
| Official gene symbol | MKLN1 |
|---|---|
| Entrez ID | 4289 |
| Gene full name | muskelin 1, intracellular mediator containing kelch motifs |
| Other gene symbols | TWA2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0007165 | Signal transduction | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0082527032 | 0.9874863417 | 0.2352350649 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1240047029 |
| GSE13712_SHEAR | Up | 0.2077347747 |
| GSE13712_STATIC | Up | 0.2497212126 |
| GSE19018 | Up | 0.0066926866 |
| GSE19899_A1 | Up | 0.5087283548 |
| GSE19899_A2 | Up | 0.3298448723 |
| PubMed_21979375_A1 | Up | 0.9778878015 |
| PubMed_21979375_A2 | Up | 0.9566956195 |
| GSE35957 | Up | 0.1142846218 |
| GSE36640 | Up | 0.1397192001 |
| GSE54402 | Up | 0.4235344480 |
| GSE9593 | Up | 0.0566579476 |
| GSE43922 | Up | 0.6357569802 |
| GSE24585 | Up | 0.2356735689 |
| GSE37065 | Up | 0.4620740834 |
| GSE28863_A1 | Up | 0.4396144659 |
| GSE28863_A2 | Up | 0.9703380710 |
| GSE28863_A3 | Down | -0.5413828972 |
| GSE28863_A4 | Down | -0.2379724902 |
| GSE48662 | Up | 0.2255994029 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-128-3p | MIMAT0000424 | MIRT022004 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022639 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-101-3p | MIMAT0000099 | MIRT027314 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-27a-3p | MIMAT0000084 | MIRT028726 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-320b | MIMAT0005792 | MIRT036235 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043148 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048420 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
