HCSGD entry for ASAH1
1. General information
| Official gene symbol | ASAH1 |
|---|---|
| Entrez ID | 427 |
| Gene full name | N-acylsphingosine amidohydrolase (acid ceramidase) 1 |
| Other gene symbols | AC ACDase ASAH PHP PHP32 SMAPME |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | TAS | molecular_function |
| GO:0005764 | Lysosome | IEA | cellular_component |
| GO:0006629 | Lipid metabolic process | IEA | biological_process |
| GO:0006665 | Sphingolipid metabolic process | TAS | biological_process |
| GO:0006672 | Ceramide metabolic process | TAS | biological_process |
| GO:0006687 | Glycosphingolipid metabolic process | TAS | biological_process |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0010033 | Response to organic substance | IEA | biological_process |
| GO:0016787 | Hydrolase activity | IEA | molecular_function |
| GO:0017040 | Ceramidase activity | TAS | molecular_function |
| GO:0030324 | Lung development | IEA | biological_process |
| GO:0043202 | Lysosomal lumen | TAS | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0791464154 | 0.4085610159 | 0.5923630861 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3106599769 |
| GSE13712_SHEAR | Down | -0.9148071057 |
| GSE13712_STATIC | Down | -0.8579377907 |
| GSE19018 | Up | 0.1207037984 |
| GSE19899_A1 | Down | -0.2974832555 |
| GSE19899_A2 | Up | 0.2316272474 |
| PubMed_21979375_A1 | Down | -0.4881753587 |
| PubMed_21979375_A2 | Up | 0.1978896660 |
| GSE35957 | Up | 0.5800320580 |
| GSE36640 | Up | 1.4224370006 |
| GSE54402 | Down | -0.5633036704 |
| GSE9593 | Up | 0.8430686718 |
| GSE43922 | Up | 0.0658796262 |
| GSE24585 | Up | 0.3641753482 |
| GSE37065 | Up | 0.3192558674 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.2830121614 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT019198 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT048957 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
