HCSGD entry for MGP
1. General information
| Official gene symbol | MGP |
|---|---|
| Entrez ID | 4256 |
| Gene full name | matrix Gla protein |
| Other gene symbols | MGLAP NTI |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001502 | Cartilage condensation | TAS | biological_process |
| GO:0001503 | Ossification | IEA | biological_process |
| GO:0005201 | Extracellular matrix structural constituent | TAS | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005578 | Proteinaceous extracellular matrix | TAS | cellular_component |
| GO:0008147 | Structural constituent of bone | TAS | molecular_function |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0030500 | Regulation of bone mineralization | IEA | biological_process |
| GO:0031012 | Extracellular matrix | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1377455872 | 0.0119052392 | 0.7475467216 | 0.2155143054 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4596948263 |
| GSE13712_SHEAR | Down | -3.9236924539 |
| GSE13712_STATIC | Down | -2.1675434142 |
| GSE19018 | Up | 0.1123007229 |
| GSE19899_A1 | Up | 0.0885463491 |
| GSE19899_A2 | Down | -0.0827700887 |
| PubMed_21979375_A1 | Down | -0.3426484635 |
| PubMed_21979375_A2 | Down | -0.2401042438 |
| GSE35957 | Down | -0.7329512496 |
| GSE36640 | Up | 1.0389175968 |
| GSE54402 | Down | -0.1195167191 |
| GSE9593 | Down | -0.3650881501 |
| GSE43922 | Up | 0.0174332408 |
| GSE24585 | Down | -0.0061716815 |
| GSE37065 | Down | -0.1588591927 |
| GSE28863_A1 | Down | -0.2884517687 |
| GSE28863_A2 | Down | -0.0349659173 |
| GSE28863_A3 | Up | 0.6237265199 |
| GSE28863_A4 | Up | 0.1028195777 |
| GSE48662 | Up | 0.4636829770 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017975 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029487 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 22379366 | With space flight there are significant reductions of serum Mg (P < 0 |
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