HCSGD entry for MEP1B
1. General information
| Official gene symbol | MEP1B |
|---|---|
| Entrez ID | 4225 |
| Gene full name | meprin A, beta |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004222 | Metalloendopeptidase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005615 | Extracellular space | TAS | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0006954 | Inflammatory response | IEA | biological_process |
| GO:0007586 | Digestion | TAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016020 | Membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6564022985 | 0.8457517989 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1007751769 |
| GSE13712_SHEAR | Up | 0.0562770777 |
| GSE13712_STATIC | Down | -0.1323138330 |
| GSE19018 | Up | 0.0995157763 |
| GSE19899_A1 | Up | 0.1914949571 |
| GSE19899_A2 | Up | 0.0619077465 |
| PubMed_21979375_A1 | Down | -0.0724254170 |
| PubMed_21979375_A2 | Down | -0.0849589863 |
| GSE35957 | Up | 0.2321949416 |
| GSE36640 | Up | 0.1653785249 |
| GSE54402 | Up | 0.0359749101 |
| GSE9593 | Down | -0.1041677013 |
| GSE43922 | Up | 0.0118004408 |
| GSE24585 | Down | -0.1532650965 |
| GSE37065 | Down | -0.0313465283 |
| GSE28863_A1 | Down | -0.0793518784 |
| GSE28863_A2 | Up | 0.0747953586 |
| GSE28863_A3 | Up | 0.1808999356 |
| GSE28863_A4 | Up | 0.0320409174 |
| GSE48662 | Up | 0.0271422104 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019267 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
