HCSGD entry for MB
1. General information
| Official gene symbol | MB |
|---|---|
| Entrez ID | 4151 |
| Gene full name | myoglobin |
| Other gene symbols | PVALB |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001666 | Response to hypoxia | IEA | biological_process |
| GO:0005344 | Oxygen transporter activity | IEA | molecular_function |
| GO:0005506 | Iron ion binding | IEA | molecular_function |
| GO:0007507 | Heart development | IEA | biological_process |
| GO:0009725 | Response to hormone | IEA | biological_process |
| GO:0019825 | Oxygen binding | IEA | molecular_function |
| GO:0020037 | Heme binding | IEA | molecular_function |
| GO:0031444 | Slow-twitch skeletal muscle fiber contraction | IEA | biological_process |
| GO:0042542 | Response to hydrogen peroxide | IEA | biological_process |
| GO:0043353 | Enucleate erythrocyte differentiation | IEA | biological_process |
| GO:0050873 | Brown fat cell differentiation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7523485734 | 0.3344974659 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0473316177 |
| GSE13712_SHEAR | Down | -0.2421974017 |
| GSE13712_STATIC | Down | -0.1301111203 |
| GSE19018 | Down | -0.0763820068 |
| GSE19899_A1 | Down | -0.0660257350 |
| GSE19899_A2 | Down | -0.1144188932 |
| PubMed_21979375_A1 | Down | -0.0026158607 |
| PubMed_21979375_A2 | Up | 0.0159870907 |
| GSE35957 | Up | 0.4428690135 |
| GSE36640 | Up | 0.0560666204 |
| GSE54402 | Down | -0.1028480127 |
| GSE9593 | Up | 0.1075953984 |
| GSE43922 | Up | 0.1318647458 |
| GSE24585 | Down | -0.1240910698 |
| GSE37065 | Down | -0.0730321764 |
| GSE28863_A1 | Down | -0.3885693620 |
| GSE28863_A2 | Down | -0.2619934056 |
| GSE28863_A3 | Up | 0.5237662628 |
| GSE28863_A4 | Down | -0.1080736919 |
| GSE48662 | Up | 0.0705395116 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Porphyrin Fe(Iii) | DB01710 | EXPT02632 |
| N-Butyl Isocyanide | DB01826 | EXPT02302 |
| Biliverdine Ix Alpha | DB02073 | EXPT00714 |
| Beta-D-Glucose | DB02379 | EXPT00685 | EXPT00455 | EXPT01603 |
| Methylethylamine | DB02396 | EXPT01370 |
| Tetrazolyl Histidine | DB02528 | EXPT02402 |
| Nitrosoethane | DB02646 | EXPT02372 |
| 1-Methylimidazole | DB02671 | EXPT00077 |
| 4-Methylimidazole | DB03385 | EXPT00221 |
| Ethyl Isocyanide | DB03399 | EXPT01344 |
| N-Propyl Isocyanide | DB04050 | EXPT02384 |
| Methyl Isocyanide | DB04337 | EXPT02202 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029607 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 12940938 | Unlike HbO2 and its separated haemoglobin chains, monomeric bovine heart myoglobin (MbO2) did not easily form hemichrome |
| 6621064 | Hemoglobin, myoglobin and other heme proteins bind thyroid hormone progressively with time and in a poorly-dissociable manner |
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