HCSGD entry for MAT1A

1. General information

Official gene symbolMAT1A
Entrez ID4143
Gene full namemethionine adenosyltransferase I, alpha
Other gene symbolsMAT MATA1 SAMS SAMS1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000096Sulfur amino acid metabolic processTASbiological_process
GO:0004478Methionine adenosyltransferase activityIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005829CytosolTAScellular_component
GO:0006520Cellular amino acid metabolic processTASbiological_process
GO:0006556S-adenosylmethionine biosynthetic processIEAbiological_process
GO:0006730One-carbon metabolic processIEAbiological_process
GO:0006805Xenobiotic metabolic processTASbiological_process
GO:0032259MethylationTASbiological_process
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.26878976480.95170037610.96568298081.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0412717595
GSE13712_SHEARUp0.1813085628
GSE13712_STATICUp0.2261503249
GSE19018Up0.0872991949
GSE19899_A1Up0.1766879358
GSE19899_A2Up0.1570816550
PubMed_21979375_A1Down-0.2585537060
PubMed_21979375_A2Up0.0086580567
GSE35957Up0.3166590338
GSE36640Up0.1216899642
GSE54402Up0.0080612977
GSE9593Up0.0209257135
GSE43922Up0.0250129268
GSE24585Up0.2046530211
GSE37065Down-0.0166824841
GSE28863_A1Down-0.0765718346
GSE28863_A2Down-0.0795432802
GSE28863_A3Up0.3297685128
GSE28863_A4Up0.2154605327
GSE48662Down-0.0725327852

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

3-Oxiran-2ylalanineDB03191 EXPT02037
L-2-Amino-4-Methoxy-Cis-but-3-Enoic AcidDB03611 EXPT00504

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018853MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.