HCSGD entry for MARK3
1. General information
| Official gene symbol | MARK3 |
|---|---|
| Entrez ID | 4140 |
| Gene full name | MAP/microtubule affinity-regulating kinase 3 |
| Other gene symbols | CTAK1 KP78 PAR1A Par-1a |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004672 | Protein kinase activity | IEA | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0016301 | Kinase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5996440865 | 0.5458629307 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3383151449 |
| GSE13712_SHEAR | Up | 0.5569717137 |
| GSE13712_STATIC | Up | 0.2008730249 |
| GSE19018 | Up | 0.0678593668 |
| GSE19899_A1 | Down | -0.0079493364 |
| GSE19899_A2 | Up | 0.0952322797 |
| PubMed_21979375_A1 | Up | 0.1131692091 |
| PubMed_21979375_A2 | Up | 0.1229072671 |
| GSE35957 | Down | -0.2734367611 |
| GSE36640 | Down | -0.0380765743 |
| GSE54402 | Up | 0.1319410471 |
| GSE9593 | Down | -0.3959179003 |
| GSE43922 | Up | 0.0372497093 |
| GSE24585 | Up | 0.1855661926 |
| GSE37065 | Up | 0.0045513093 |
| GSE28863_A1 | Up | 0.1316931684 |
| GSE28863_A2 | Up | 0.1152409001 |
| GSE28863_A3 | Down | -0.4245146616 |
| GSE28863_A4 | Down | -0.0859831889 |
| GSE48662 | Down | -0.0644904250 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-331-3p | MIMAT0000760 | MIRT043531 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
