HCSGD entry for MANBA
1. General information
| Official gene symbol | MANBA |
|---|---|
| Entrez ID | 4126 |
| Gene full name | mannosidase, beta A, lysosomal |
| Other gene symbols | MANB1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004567 | Beta-mannosidase activity | IEA | molecular_function |
| GO:0005537 | Mannose binding | IEA | molecular_function |
| GO:0005764 | Lysosome | IEA | cellular_component |
| GO:0006464 | Cellular protein modification process | NAS | biological_process |
| GO:0006516 | Glycoprotein catabolic process | IEA | biological_process |
| GO:0046355 | Mannan catabolic process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1549513506 | 0.1075149082 | 0.7823568278 | 0.6274722616 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3072842311 |
| GSE13712_SHEAR | Down | -1.1191385556 |
| GSE13712_STATIC | Down | -0.5298471412 |
| GSE19018 | Up | 0.7399568815 |
| GSE19899_A1 | Down | -0.5139413822 |
| GSE19899_A2 | Down | -0.8454701450 |
| PubMed_21979375_A1 | Down | -0.7818255129 |
| PubMed_21979375_A2 | Up | 0.0873670621 |
| GSE35957 | Up | 0.7511948972 |
| GSE36640 | Up | 1.2441410446 |
| GSE54402 | Down | -0.5792195216 |
| GSE9593 | Up | 1.0203199432 |
| GSE43922 | Up | 0.0352948157 |
| GSE24585 | Up | 0.1593230795 |
| GSE37065 | Up | 0.2591117933 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.1390023722 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017002 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
