HCSGD entry for MAN2A1

1. General information

Official gene symbolMAN2A1
Entrez ID4124
Gene full namemannosidase, alpha, class 2A, member 1
Other gene symbolsGOLIM7 MANA2 MANII
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneTAScellular_component
GO:0001701In utero embryonic developmentIEAbiological_process
GO:0001889Liver developmentIEAbiological_process
GO:0004572Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activityIEAmolecular_function
GO:0006013Mannose metabolic processIEAbiological_process
GO:0006491N-glycan processingIEAbiological_process
GO:0007005Mitochondrion organizationIEAbiological_process
GO:0007033Vacuole organizationIEAbiological_process
GO:0007585Respiratory gaseous exchangeIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0016799Hydrolase activity, hydrolyzing N-glycosyl compoundsIEAmolecular_function
GO:0018279Protein N-linked glycosylation via asparagineTASbiological_process
GO:0030246Carbohydrate bindingIEAmolecular_function
GO:0043687Post-translational protein modificationTASbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0048286Lung alveolus developmentIEAbiological_process
GO:0050769Positive regulation of neurogenesisIEAbiological_process
GO:0060042Retina morphogenesis in camera-type eyeIEAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.01551475630.67142657190.30957416921.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.6757946826
GSE13712_SHEARDown-0.0912629029
GSE13712_STATICDown-0.2907193132
GSE19018Up0.9036572712
GSE19899_A1Up0.7580941367
GSE19899_A2Down-0.1438833091
PubMed_21979375_A1Up0.2284436476
PubMed_21979375_A2Up0.5539612293
GSE35957Up0.1524639488
GSE36640Up0.9917873966
GSE54402Up0.1219654928
GSE9593Down-0.5324789660
GSE43922Up0.5012182989
GSE24585Up0.2505387389
GSE37065Down-0.1578038318
GSE28863_A1Up0.4194562971
GSE28863_A2Up0.4740074962
GSE28863_A3Down-0.6640436515
GSE28863_A4Down-0.0584096815
GSE48662Down-0.6981632447

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

SwainsonineDB02034 EXPT02983
2-Deoxy-2-Fluoro-Alpha-D-Mannosyl FluorideDB02318 EXPT01456
GhavamiolDB02492 EXPT01590
KifunensineDB02742 EXPT01973
5-Fluoro-Beta-L-Gulosyl FluorideDB03008 EXPT01670
5-Thio-a/B-D-MannopyranosylamineDB03414 EXPT02038
1-deoxymannojirimycinDB03955 EXPT01145
(1R,2R,3R,4S,5R)-4-(BENZYLAMINO)-5-(METHYLTHIO)CYCLOPENTANE-1,2,3-TRIOLDB06984 -
(1S,2S,3R,6R)-4-(hydroxymethyl)-6-(octylamino)cyclohex-4-ene-1,2,3-triolDB08321 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT002612MicroarrayFunctional MTI (Weak)18668037
hsa-miR-124-3pMIMAT0000422MIRT002612MicroarrayFunctional MTI (Weak)15685193
hsa-miR-320aMIMAT0000510MIRT044543CLASHFunctional MTI (Weak)23622248
hsa-miR-149-5pMIMAT0000450MIRT045458CLASHFunctional MTI (Weak)23622248
Entries Per Page
Displaying Page of
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.