HCSGD entry for MAN1A1
1. General information
| Official gene symbol | MAN1A1 |
|---|---|
| Entrez ID | 4121 |
| Gene full name | mannosidase, alpha, class 1A, member 1 |
| Other gene symbols | HUMM3 HUMM9 MAN9 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | cellular_component |
| GO:0004571 | Mannosyl-oligosaccharide 1,2-alpha-mannosidase activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005783 | Endoplasmic reticulum | TAS | cellular_component |
| GO:0005793 | Endoplasmic reticulum-Golgi intermediate compartment | IDA | cellular_component |
| GO:0015923 | Mannosidase activity | TAS | molecular_function |
| GO:0016020 | Membrane | IEA TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0018279 | Protein N-linked glycosylation via asparagine | TAS | biological_process |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0712333536 | 0.0728666350 | 0.5692304915 | 0.5090028397 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4037122413 |
| GSE13712_SHEAR | Down | -0.9508309155 |
| GSE13712_STATIC | Down | -0.6597677216 |
| GSE19018 | Down | -0.8795744385 |
| GSE19899_A1 | Down | -0.0801423070 |
| GSE19899_A2 | Down | -1.0698721306 |
| PubMed_21979375_A1 | Up | 0.8517309422 |
| PubMed_21979375_A2 | Down | -0.2129161036 |
| GSE35957 | Up | 0.8926380745 |
| GSE36640 | Up | 0.6923189363 |
| GSE54402 | Up | 0.2057442610 |
| GSE9593 | Up | 0.6354171712 |
| GSE43922 | Down | -0.2150281870 |
| GSE24585 | Down | -0.1498399418 |
| GSE37065 | Up | 0.2929140451 |
| GSE28863_A1 | Up | 0.8385183182 |
| GSE28863_A2 | Up | 0.9155392747 |
| GSE28863_A3 | Down | -0.0926325151 |
| GSE28863_A4 | Down | -0.3007726829 |
| GSE48662 | Down | -0.5206887960 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017036 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-125b-5p | MIMAT0000423 | NA | hsa-miR-125b | 18056640 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
