HCSGD entry for STS
1. General information
| Official gene symbol | STS |
|---|---|
| Entrez ID | 412 |
| Gene full name | steroid sulfatase (microsomal), isozyme S |
| Other gene symbols | ARSC ARSC1 ASC ES SSDD XLI |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004773 | Steryl-sulfatase activity | TAS | molecular_function |
| GO:0005764 | Lysosome | TAS | cellular_component |
| GO:0005768 | Endosome | TAS | cellular_component |
| GO:0005783 | Endoplasmic reticulum | TAS | cellular_component |
| GO:0005788 | Endoplasmic reticulum lumen | TAS | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0005794 | Golgi apparatus | TAS | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006665 | Sphingolipid metabolic process | TAS | biological_process |
| GO:0006687 | Glycosphingolipid metabolic process | TAS | biological_process |
| GO:0006706 | Steroid catabolic process | TAS | biological_process |
| GO:0007565 | Female pregnancy | IEA | biological_process |
| GO:0008484 | Sulfuric ester hydrolase activity | IDA | molecular_function |
| GO:0008544 | Epidermis development | TAS | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0043231 | Intracellular membrane-bounded organelle | TAS | cellular_component |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0219910794 | 0.7735978268 | 0.3553758134 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0291775403 |
| GSE13712_SHEAR | Up | 0.3529585505 |
| GSE13712_STATIC | Up | 0.0799841613 |
| GSE19018 | Down | -0.0685259380 |
| GSE19899_A1 | Down | -0.1670725982 |
| GSE19899_A2 | Down | -0.0063682538 |
| PubMed_21979375_A1 | Up | 0.5256228412 |
| PubMed_21979375_A2 | Up | 0.5063249270 |
| GSE35957 | Up | 0.4474365663 |
| GSE36640 | Up | 1.3812969970 |
| GSE54402 | Down | -0.6105623624 |
| GSE9593 | Up | 1.0753282686 |
| GSE43922 | Up | 0.0486781716 |
| GSE24585 | Down | -0.6193954396 |
| GSE37065 | Up | 0.3785807516 |
| GSE28863_A1 | Up | 0.4709689340 |
| GSE28863_A2 | Up | 0.8265034022 |
| GSE28863_A3 | Down | -0.0474459818 |
| GSE28863_A4 | Up | 0.1768405467 |
| GSE48662 | Up | 0.0841673073 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| 2-Amino-3-Oxo-4-Sulfo-Butyric Acid | DB02735 | EXPT00503 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019334 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 23535008 | Soft tissue sarcomas (STS) are characterized by co-participation of several epigenetic and genetic events during tumorigenesis |
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