HCSGD entry for MAL

1. General information

Official gene symbolMAL
Entrez ID4118
Gene full namemal, T-cell differentiation protein
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001766Membrane raft polarizationTASbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005768EndosomeTAScellular_component
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006810TransportTASbiological_process
GO:0006915Apoptotic processNASbiological_process
GO:0007417Central nervous system developmentTASbiological_process
GO:0008289Lipid bindingTASmolecular_function
GO:0010952Positive regulation of peptidase activityNASbiological_process
GO:0015267Channel activityTASmolecular_function
GO:0016324Apical plasma membraneTAScellular_component
GO:0016505Peptidase activator activity involved in apoptotic processNASmolecular_function
GO:0019898Extrinsic component of membraneIEAcellular_component
GO:0019911Structural constituent of myelin sheathIDAmolecular_function
GO:0030154Cell differentiationTASbiological_process
GO:0042552MyelinationNAS TASbiological_process
GO:0043085Positive regulation of catalytic activityNASbiological_process
GO:0045121Membrane raftIDAcellular_component
GO:0045176Apical protein localizationTASbiological_process
GO:0050790Regulation of catalytic activityNASbiological_process
GO:0052547Regulation of peptidase activityNASbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:1902043Positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.23879032710.96183783670.92461881441.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0777058938
GSE13712_SHEARDown-0.0817071787
GSE13712_STATICUp0.0537223523
GSE19018Up0.1171164522
GSE19899_A1Up0.0029808074
GSE19899_A2Up0.1332444703
PubMed_21979375_A1Down-0.0343250711
PubMed_21979375_A2Down-0.0780853283
GSE35957Up0.0894535236
GSE36640Up0.0863266869
GSE54402Up0.0554960214
GSE9593Down-0.0067213499
GSE43922Up0.0517189598
GSE24585Up0.4997825076
GSE37065Up0.0756988078
GSE28863_A1Up0.0242151829
GSE28863_A2Up0.0848591516
GSE28863_A3Up0.2608337975
GSE28863_A4Up0.2358008996
GSE48662Up0.0957797562

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.