HCSGD entry for MXD1
1. General information
| Official gene symbol | MXD1 |
|---|---|
| Entrez ID | 4084 |
| Gene full name | MAX dimerization protein 1 |
| Other gene symbols | BHLHC58 MAD MAD1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | TAS | molecular_function |
| GO:0003712 | Transcription cofactor activity | TAS | molecular_function |
| GO:0003714 | Transcription corepressor activity | TAS | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007275 | Multicellular organismal development | TAS | biological_process |
| GO:0008283 | Cell proliferation | TAS | biological_process |
| GO:0046983 | Protein dimerization activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0014897382 | 0.9814074883 | 0.1040090186 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4247055925 |
| GSE13712_SHEAR | Up | 0.7725006979 |
| GSE13712_STATIC | Down | -0.0759055262 |
| GSE19018 | Down | -0.3201466586 |
| GSE19899_A1 | Up | 0.5068947879 |
| GSE19899_A2 | Up | 1.3203617774 |
| PubMed_21979375_A1 | Up | 0.6331187259 |
| PubMed_21979375_A2 | Up | 1.8489337199 |
| GSE35957 | Up | 0.1345880371 |
| GSE36640 | Up | 2.3969996449 |
| GSE54402 | Up | 0.7134124395 |
| GSE9593 | Up | 0.4550091108 |
| GSE43922 | Up | 1.3879287441 |
| GSE24585 | Up | 0.3792414497 |
| GSE37065 | Up | 0.1347972947 |
| GSE28863_A1 | Down | -0.1858157093 |
| GSE28863_A2 | Up | 0.1482488066 |
| GSE28863_A3 | Down | -0.1167230759 |
| GSE28863_A4 | Down | -0.2419162937 |
| GSE48662 | Up | 0.5798880161 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-138-5p | MIMAT0000430 | MIRT006866 | Luciferase reporter assay//Microarray | Functional MTI | 22921398 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT017596 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
