HCSGD entry for NBR1
1. General information
| Official gene symbol | NBR1 |
|---|---|
| Entrez ID | 4077 |
| Gene full name | neighbor of BRCA1 gene 1 |
| Other gene symbols | 1A1-3B M17S2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000407 | Pre-autophagosomal structure | IEA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005764 | Lysosome | IEA | cellular_component |
| GO:0005770 | Late endosome | ISS | cellular_component |
| GO:0005776 | Autophagic vacuole | ISS | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016236 | Macroautophagy | IDA | biological_process |
| GO:0030500 | Regulation of bone mineralization | ISS | biological_process |
| GO:0031410 | Cytoplasmic vesicle | IEA | cellular_component |
| GO:0031430 | M band | IEA | cellular_component |
| GO:0032872 | Regulation of stress-activated MAPK cascade | ISS | biological_process |
| GO:0043130 | Ubiquitin binding | IDA | molecular_function |
| GO:0045668 | Negative regulation of osteoblast differentiation | ISS | biological_process |
| GO:0051019 | Mitogen-activated protein kinase binding | ISS | molecular_function |
| GO:0051259 | Protein oligomerization | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0677513620 | 0.9388236997 | 0.5596405897 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0947823133 |
| GSE13712_SHEAR | Down | -0.0281298979 |
| GSE13712_STATIC | Down | -0.0640634360 |
| GSE19018 | Up | 0.5007453874 |
| GSE19899_A1 | Down | -0.0232122576 |
| GSE19899_A2 | Up | 0.0642492549 |
| PubMed_21979375_A1 | Down | -0.7952479510 |
| PubMed_21979375_A2 | Up | 0.0295610984 |
| GSE35957 | Down | -0.0909082554 |
| GSE36640 | Up | 0.8310014117 |
| GSE54402 | Up | 0.2287478021 |
| GSE9593 | Up | 0.2711293131 |
| GSE43922 | Down | -0.1480667782 |
| GSE24585 | Up | 0.5990132562 |
| GSE37065 | Down | -0.0316315066 |
| GSE28863_A1 | Up | 0.7100231969 |
| GSE28863_A2 | Up | 0.3473725244 |
| GSE28863_A3 | Up | 0.1391356149 |
| GSE28863_A4 | Up | 0.0132370086 |
| GSE48662 | Up | 0.0805303623 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-615-3p | MIMAT0003283 | MIRT039971 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040928 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049785 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050957 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
