HCSGD entry for EPCAM
1. General information
| Official gene symbol | EPCAM |
|---|---|
| Entrez ID | 4072 |
| Gene full name | epithelial cell adhesion molecule |
| Other gene symbols | DIAR5 EGP-2 EGP314 EGP40 ESA HNPCC8 KS1/4 KSA M4S1 MIC18 MK-1 TACSTD1 TROP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001657 | Ureteric bud development | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0005923 | Tight junction | IDA | cellular_component |
| GO:0008284 | Positive regulation of cell proliferation | IDA | biological_process |
| GO:0009986 | Cell surface | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016323 | Basolateral plasma membrane | IDA | cellular_component |
| GO:0016324 | Apical plasma membrane | IDA | cellular_component |
| GO:0016328 | Lateral plasma membrane | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8383069792 | 0.0917827172 | 0.9999902473 | 0.5763833015 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0929188275 |
| GSE13712_SHEAR | Down | -0.3904042795 |
| GSE13712_STATIC | Up | 0.3621242949 |
| GSE19018 | Up | 0.1820509522 |
| GSE19899_A1 | Down | -0.1452144455 |
| GSE19899_A2 | Down | -0.2731941012 |
| PubMed_21979375_A1 | Up | 1.0497690107 |
| PubMed_21979375_A2 | Down | -0.0458081334 |
| GSE35957 | Down | -0.0938399562 |
| GSE36640 | Down | -1.8574064054 |
| GSE54402 | Down | -0.9794980321 |
| GSE9593 | Up | 0.0076392903 |
| GSE43922 | Down | -0.1605531241 |
| GSE24585 | Down | -0.3321173638 |
| GSE37065 | Down | -0.0255571457 |
| GSE28863_A1 | Down | -0.0573446437 |
| GSE28863_A2 | Up | 0.2099266406 |
| GSE28863_A3 | Up | 0.1434952063 |
| GSE28863_A4 | Down | -0.0350939188 |
| GSE48662 | Down | -0.1295039176 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 25046437 | Isolated PSC cells expressed cholangiocyte (eg, cytokeratin 7 and 19) and epithelial cell adhesion markers (EPCAM, ICAM) and were negative for hepatocyte and myofibroblast markers (albumin, alpha-actin) |
| 21521500 | Putative progenitor cell populations were isolated based on co-expression or concomitant absence of the epithelial and myoepithelial markers EPCAM and CALLA respectively |
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