HCSGD entry for MIR184
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
Not in the Gene Ontology
4. Expression levels in datasets
Individual experiment result ( "-" represent NA in the specific microarray platform )
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles:
1 abstracts the gene occurs . PubMed ID of the article Sentenece the gene occurs 26165933 Rat renal primary glomerular mesangial cells (GMCs) were isolated from 3-month and 24-month-old rats for the in vitro analysis of the roles of miR-184 and miR-150 in kidney aging 26165933 Bioinformatics analyses suggested that Rab1a and Rab31, which are associated with cell autophagy, were targeted by both miR-184 and miR-150 26165933 Furthermore, dual luciferase reporter assays revealed that miR-184 and miR-150 bound to the 3'-UTR of Rab1a and Rab31 mRNAs 26165933 Transfection of miR-184 and miR-150 mimics into young GMCs suppressed the expression of Rab1a and Rab31 26165933 However, miR-184 and miR-150 inhibitors promoted autophagy and reduced oxidative damage by upregulating Rab1a and Rab31 in old GMCs 26165933 In conclusion, miR-184 and miR-150 inhibited autophagy, promoting GMC aging
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