HCSGD entry for LYZ

1. General information

Official gene symbolLYZ
Entrez ID4069
Gene full namelysozyme
Other gene symbolsLZM
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003796Lysozyme activityIEA TASmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceTAScellular_component
GO:0006954Inflammatory responseTASbiological_process
GO:0016998Cell wall macromolecule catabolic processIEAbiological_process
GO:0019835CytolysisIEAbiological_process
GO:0042742Defense response to bacteriumIEAbiological_process
GO:0042802Identical protein bindingIPImolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.14533569390.63743282930.76431918081.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.5836123519
GSE13712_SHEARUp0.0088086958
GSE13712_STATICDown-0.1216807453
GSE19018Up0.0478929219
GSE19899_A1Up0.0382832078
GSE19899_A2Up0.2902889743
PubMed_21979375_A1Up0.4609989476
PubMed_21979375_A2Up0.2493348957
GSE35957Down-1.4260134093
GSE36640Up0.1833240377
GSE54402Up0.0328140685
GSE9593Down-1.2447137770
GSE43922Up0.8095213725
GSE24585Up0.0866778685
GSE37065Down-0.1051756008
GSE28863_A1Down-0.1372663727
GSE28863_A2Down-0.0646232680
GSE28863_A3Up0.0868581265
GSE28863_A4Up0.3109558429
GSE48662--

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-Aspartic AcidDB00128 NUTR00016 | EXPT01823
(R)-Propylene glycolDB02159 EXPT02574
Cu-BicyclamDB02250 EXPT02192
4-Methylumbelliferyl ChitobioseDB02759 EXPT01671
SucroseDB02772 EXPT02977
Arsanilic acidDB03006 EXPT00575
Di(N-Acetyl-D-Glucosamine)DB03013 EXPT00851
Para-Toluene SulfonateDB03120 EXPT03125
1-ProponolDB03175 EXPT02630
Cu-CyclamDB03189 EXPT02191
3-AminosuccinimideDB03487 EXPT02930
Dodecyl SulfateDB03967 EXPT02877
ChitotrioseDB04194 EXPT01052
Methylumbelliferyl ChitotrioseDB04268 EXPT03186
UNDECA-3,7-DIENE-1,3,7,11-TETRACARBALDEHYDEDB06912 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT030049MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.