HCSGD entry for LTBR
1. General information
| Official gene symbol | LTBR |
|---|---|
| Entrez ID | 4055 |
| Gene full name | lymphotoxin beta receptor (TNFR superfamily, member 3) |
| Other gene symbols | CD18 D12S370 LT-BETA-R TNF-R-III TNFCR TNFR-RP TNFR2-RP TNFR3 TNFRSF3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0031625 | Ubiquitin protein ligase binding | IPI | molecular_function |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0043123 | Positive regulation of I-kappaB kinase/NF-kappaB signaling | IEP | biological_process |
| GO:0046330 | Positive regulation of JNK cascade | IMP | biological_process |
| GO:0071260 | Cellular response to mechanical stimulus | IEP | biological_process |
| GO:2001238 | Positive regulation of extrinsic apoptotic signaling pathway | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0736394134 | 0.9596974165 | 0.5767238251 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0117606663 |
| GSE13712_SHEAR | Down | -0.0077173666 |
| GSE13712_STATIC | Up | 0.1640068467 |
| GSE19018 | Down | -0.0201887734 |
| GSE19899_A1 | Up | 0.0608249400 |
| GSE19899_A2 | Up | 0.5239305090 |
| PubMed_21979375_A1 | Up | 0.6454784752 |
| PubMed_21979375_A2 | Up | 0.2390718659 |
| GSE35957 | Up | 0.0433794016 |
| GSE36640 | Up | 0.4789103762 |
| GSE54402 | Up | 0.1137252915 |
| GSE9593 | Up | 0.2028910457 |
| GSE43922 | Up | 0.3892699689 |
| GSE24585 | Down | -0.3678388435 |
| GSE37065 | Down | -0.1156072029 |
| GSE28863_A1 | Up | 0.3413678343 |
| GSE28863_A2 | Up | 0.4843861021 |
| GSE28863_A3 | Down | -0.1070792162 |
| GSE28863_A4 | Down | -0.0399395230 |
| GSE48662 | Up | 0.5736506380 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027696 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
