HCSGD entry for CYP4F3


1. General information

Official gene symbolCYP4F3
Entrez ID4051
Gene full namecytochrome P450, family 4, subfamily F, polypeptide 3
Other gene symbolsCPF3 CYP4F LTB4H
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004497Monooxygenase activityTASmolecular_function
GO:0005506Iron ion bindingIEAmolecular_function
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0006690Icosanoid metabolic processTASbiological_process
GO:0006691Leukotriene metabolic processTASbiological_process
GO:0006805Xenobiotic metabolic processTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0019369Arachidonic acid metabolic processTASbiological_process
GO:0020037Heme bindingIEAmolecular_function
GO:0044281Small molecule metabolic processTASbiological_process
GO:0050051Leukotriene-B4 20-monooxygenase activityIEAmolecular_function
GO:0052871Alpha-tocopherol omega-hydroxylase activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.38034230080.86346053720.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1677310047
GSE13712_SHEARDown-0.0321855740
GSE13712_STATICUp0.1205574957
GSE19018Up0.1328710646
GSE19899_A1Up0.1471295975
GSE19899_A2Up0.5487564895
PubMed_21979375_A1Up0.2688867270
PubMed_21979375_A2Up0.4326967058
GSE35957Up0.1952592630
GSE36640Down-0.0856457327
GSE54402Down-0.0435965712
GSE9593Up0.0873225578
GSE43922Up0.0100652471
GSE24585Up0.0831599854
GSE37065Down-0.0461574562
GSE28863_A1Down-0.1724295900
GSE28863_A2Up0.0799867069
GSE28863_A3Up0.2933452807
GSE28863_A4Down-0.0899639397
GSE48662Down-0.0279453543

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.