HCSGD entry for LTB
1. General information
| Official gene symbol | LTB |
|---|---|
| Entrez ID | 4050 |
| Gene full name | lymphotoxin beta (TNF superfamily, member 3) |
| Other gene symbols | TNFC TNFSF3 p33 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005102 | Receptor binding | TAS | molecular_function |
| GO:0005125 | Cytokine activity | IEA | molecular_function |
| GO:0005164 | Tumor necrosis factor receptor binding | IEA | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0006955 | Immune response | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007267 | Cell-cell signaling | TAS | biological_process |
| GO:0010467 | Gene expression | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0043588 | Skin development | IEA | biological_process |
| GO:0045084 | Positive regulation of interleukin-12 biosynthetic process | ISS | biological_process |
| GO:0048535 | Lymph node development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2995713651 | 0.7360712055 | 0.9988275631 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1199456968 |
| GSE13712_SHEAR | Up | 0.3370851874 |
| GSE13712_STATIC | Up | 1.0648533007 |
| GSE19018 | Up | 0.0596773097 |
| GSE19899_A1 | Up | 0.0146475702 |
| GSE19899_A2 | Up | 0.2020899996 |
| PubMed_21979375_A1 | Up | 0.0622440655 |
| PubMed_21979375_A2 | Down | -0.0944528680 |
| GSE35957 | Up | 0.0337253643 |
| GSE36640 | Up | 0.0132223001 |
| GSE54402 | Down | -0.1798674057 |
| GSE9593 | Up | 0.0109295859 |
| GSE43922 | Up | 0.0903609626 |
| GSE24585 | Up | 0.0987283802 |
| GSE37065 | Down | -0.0940864226 |
| GSE28863_A1 | Up | 0.1044400553 |
| GSE28863_A2 | Down | -0.0609454666 |
| GSE28863_A3 | Up | 0.1448394698 |
| GSE28863_A4 | Up | 0.1415997348 |
| GSE48662 | Down | -0.0919287905 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-146a-5p | MIMAT0000449 | NA | hsa-miR-146a | 19944095 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
