HCSGD entry for LPP
1. General information
| Official gene symbol | LPP |
|---|---|
| Entrez ID | 4026 |
| Gene full name | LIM domain containing preferred translocation partner in lipoma |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0005925 | Focal adhesion | IDA | cellular_component |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3632606816 | 0.0155206185 | 0.9999902473 | 0.2446159619 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.7061558374 |
| GSE13712_SHEAR | Up | 0.0767562428 |
| GSE13712_STATIC | Up | 0.2593336615 |
| GSE19018 | Down | -0.3752244746 |
| GSE19899_A1 | Down | -0.6509994225 |
| GSE19899_A2 | Down | -0.4378693324 |
| PubMed_21979375_A1 | Down | -1.0156383224 |
| PubMed_21979375_A2 | Down | -0.4239634823 |
| GSE35957 | Down | -0.1596268634 |
| GSE36640 | Down | -0.1789104577 |
| GSE54402 | Down | -0.6168989829 |
| GSE9593 | Up | 0.0706799092 |
| GSE43922 | Down | -0.6547505731 |
| GSE24585 | Down | -0.2770921721 |
| GSE37065 | Down | -0.0329170200 |
| GSE28863_A1 | Up | 1.2223118598 |
| GSE28863_A2 | Up | 1.0488588463 |
| GSE28863_A3 | Up | 0.3426420750 |
| GSE28863_A4 | Down | -0.4163542537 |
| GSE48662 | Up | 0.4537095843 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022848 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 9597752 | The hic-5 gene encodes the novel LIM protein which has been implicated in cellular senescence and differentiation processes |
| 7517666 | A new LIM protein containing an autoepitope homologous to "senescent cell antigen" |
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