HCSGD entry for SHC4
1. General information
| Official gene symbol | SHC4 |
|---|---|
| Entrez ID | 399694 |
| Gene full name | SHC (Src homology 2 domain containing) family, member 4 |
| Other gene symbols | RaLP SHCD |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0019904 | Protein domain specific binding | IEA | molecular_function |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0030971 | Receptor tyrosine kinase binding | IEA | molecular_function |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0045211 | Postsynaptic membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2627928270 | 0.0610859276 | 0.9567040111 | 0.4656364610 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.0503813523 |
| GSE13712_SHEAR | Down | -0.0495291504 |
| GSE13712_STATIC | Down | -0.0211191340 |
| GSE19018 | Down | -0.3212932395 |
| GSE19899_A1 | Down | -0.6529582593 |
| GSE19899_A2 | Down | -1.0883402883 |
| PubMed_21979375_A1 | Down | -0.3422336082 |
| PubMed_21979375_A2 | Up | 0.5121257703 |
| GSE35957 | Up | 0.0681436740 |
| GSE36640 | Up | 1.0242917383 |
| GSE54402 | Down | -1.3824444758 |
| GSE9593 | Up | 0.0411828653 |
| GSE43922 | Up | 0.0585759503 |
| GSE24585 | Up | 0.2304209631 |
| GSE37065 | Up | 0.3607540112 |
| GSE28863_A1 | Down | -0.4589390392 |
| GSE28863_A2 | Down | -0.1810239290 |
| GSE28863_A3 | Down | -0.1105115273 |
| GSE28863_A4 | Down | -0.1785157600 |
| GSE48662 | Up | 0.1267953957 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017379 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
