HCSGD entry for FADS3

1. General information

Official gene symbolFADS3
Entrez ID3995
Gene full namefatty acid desaturase 3
Other gene symbolsCYB5RP LLCDL3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003674Molecular_functionNDmolecular_function
GO:0005506Iron ion bindingIEAmolecular_function
GO:0005789Endoplasmic reticulum membraneIEAcellular_component
GO:0006629Lipid metabolic processIEAbiological_process
GO:0006633Fatty acid biosynthetic processIEAbiological_process
GO:0006636Unsaturated fatty acid biosynthetic processNASbiological_process
GO:0016020MembraneNAScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0016717Oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of waterIEAmolecular_function
GO:0020037Heme bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00762953920.76784706130.22794222471.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.5886954229
GSE13712_SHEARUp0.2889960898
GSE13712_STATICDown-0.2019074474
GSE19018Up0.6128265378
GSE19899_A1Down-0.1917701460
GSE19899_A2Up1.9395573582
PubMed_21979375_A1Up2.6176018205
PubMed_21979375_A2Up1.3606338021
GSE35957Up0.3194407950
GSE36640Up1.0078772365
GSE54402Down-0.0856761312
GSE9593Up0.6338910653
GSE43922Up0.4766416166
GSE24585Up0.0899867059
GSE37065Down-0.0532355640
GSE28863_A1Down-0.3815398613
GSE28863_A2Up0.1425878143
GSE28863_A3Down-0.1784196898
GSE28863_A4Up0.1063888004
GSE48662Up0.5833351687

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-98-5pMIMAT0000096MIRT027418MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.