HCSGD entry for LIMK2
1. General information
| Official gene symbol | LIMK2 |
|---|---|
| Entrez ID | 3985 |
| Gene full name | LIM domain kinase 2 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004672 | Protein kinase activity | IEA | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IEA TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA TAS | cellular_component |
| GO:0005737 | Cytoplasm | IEA TAS | cellular_component |
| GO:0005801 | Cis-Golgi network | IEA | cellular_component |
| GO:0007283 | Spermatogenesis | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016310 | Phosphorylation | TAS | biological_process |
| GO:0042325 | Regulation of phosphorylation | IEA | biological_process |
| GO:0046982 | Protein heterodimerization activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1615260324 | 0.4219259185 | 0.7955701160 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0934024053 |
| GSE13712_SHEAR | Down | -0.1347375211 |
| GSE13712_STATIC | Up | 0.0211586071 |
| GSE19018 | Down | -0.2014289815 |
| GSE19899_A1 | Up | 0.0649461161 |
| GSE19899_A2 | Up | 0.3724109389 |
| PubMed_21979375_A1 | Down | -0.1017482387 |
| PubMed_21979375_A2 | Up | 0.6048197116 |
| GSE35957 | Up | 0.7933751908 |
| GSE36640 | Up | 0.8333991150 |
| GSE54402 | Down | -0.2245898877 |
| GSE9593 | Down | -0.0756428951 |
| GSE43922 | Up | 0.0621113486 |
| GSE24585 | Up | 0.2729496517 |
| GSE37065 | Up | 0.0245098594 |
| GSE28863_A1 | Down | -0.3824504094 |
| GSE28863_A2 | Down | -0.4256127245 |
| GSE28863_A3 | Down | -0.1679482931 |
| GSE28863_A4 | Down | -0.1563713264 |
| GSE48662 | Up | 0.6241913168 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
