HCSGD entry for LHX1

1. General information

Official gene symbolLHX1
Entrez ID3975
Gene full nameLIM homeobox 1
Other gene symbolsLIM-1 LIM1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001655Urogenital system developmentISSbiological_process
GO:0001657Ureteric bud developmentISSbiological_process
GO:0001658Branching involved in ureteric bud morphogenesisIEAbiological_process
GO:0001702Gastrulation with mouth forming secondISSbiological_process
GO:0001705Ectoderm formationISSbiological_process
GO:0001706Endoderm formationISSbiological_process
GO:0001822Kidney developmentISSbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityISSmolecular_function
GO:0003714Transcription corepressor activityISSmolecular_function
GO:0005634NucleusISScellular_component
GO:0006366Transcription from RNA polymerase II promoterISSbiological_process
GO:0007267Cell-cell signalingISSbiological_process
GO:0007389Pattern specification processISSbiological_process
GO:0007399Nervous system developmentTASbiological_process
GO:0008045Motor neuron axon guidanceISSbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0009653Anatomical structure morphogenesisISSbiological_process
GO:0009791Post-embryonic developmentISSbiological_process
GO:0009880Embryonic pattern specificationISSbiological_process
GO:0009887Organ morphogenesisTASbiological_process
GO:0009948Anterior/posterior axis specificationISSbiological_process
GO:0009952Anterior/posterior pattern specificationISSbiological_process
GO:0009953Dorsal/ventral pattern formationISSbiological_process
GO:0010468Regulation of gene expressionISSbiological_process
GO:0010842Retina layer formationISSbiological_process
GO:0021517Ventral spinal cord developmentIEAbiological_process
GO:0021527Spinal cord association neuron differentiationISSbiological_process
GO:0021537Telencephalon developmentIEAbiological_process
GO:0021549Cerebellum developmentISSbiological_process
GO:0021702Cerebellar Purkinje cell differentiationISSbiological_process
GO:0021871Forebrain regionalizationISSbiological_process
GO:0021937Cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferationISSbiological_process
GO:0032525Somite rostral/caudal axis specificationIEAbiological_process
GO:0035502Metanephric part of ureteric bud developmentIEAbiological_process
GO:0035846Oviduct epithelium developmentISSbiological_process
GO:0035847Uterine epithelium developmentISSbiological_process
GO:0035849Nephric duct elongationIEAbiological_process
GO:0035852Horizontal cell localizationIEAbiological_process
GO:0040019Positive regulation of embryonic developmentISSbiological_process
GO:0043234Protein complexISScellular_component
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0044344Cellular response to fibroblast growth factor stimulusIEAbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedISSbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedISSbiological_process
GO:0048646Anatomical structure formation involved in morphogenesisISSbiological_process
GO:0048703Embryonic viscerocranium morphogenesisISSbiological_process
GO:0048793Pronephros developmentIEAbiological_process
GO:0060059Embryonic retina morphogenesis in camera-type eyeISSbiological_process
GO:0060065Uterus developmentISSbiological_process
GO:0060066Oviduct developmentISSbiological_process
GO:0060067Cervix developmentISSbiological_process
GO:0060068Vagina developmentISSbiological_process
GO:0060322Head developmentISSbiological_process
GO:0060429Epithelium developmentISSbiological_process
GO:0061205Paramesonephric duct developmentISSbiological_process
GO:0072049Comma-shaped body morphogenesisISSbiological_process
GO:0072050S-shaped body morphogenesisISSbiological_process
GO:0072077Renal vesicle morphogenesisISSbiological_process
GO:0072177Mesonephric duct developmentIEAbiological_process
GO:0072178Nephric duct morphogenesisISSbiological_process
GO:0072224Metanephric glomerulus developmentIEAbiological_process
GO:0072278Metanephric comma-shaped body morphogenesisIEAbiological_process
GO:0072283Metanephric renal vesicle morphogenesisIEAbiological_process
GO:0072284Metanephric S-shaped body morphogenesisIEAbiological_process
GO:0090009Primitive streak formationISSbiological_process
GO:0090190Positive regulation of branching involved in ureteric bud morphogenesisISSbiological_process
GO:0097477Lateral motor column neuron migrationISSbiological_process
GO:2000543Positive regulation of gastrulationISSbiological_process
GO:2000744Positive regulation of anterior head developmentISSbiological_process
GO:2000768Positive regulation of nephron tubule epithelial cell differentiationISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.33526634250.68092223700.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1480708730
GSE13712_SHEARDown-0.0594500277
GSE13712_STATICUp0.2751088314
GSE19018Up0.1172937952
GSE19899_A1Down-0.0784162516
GSE19899_A2Up0.1040168603
PubMed_21979375_A1Down-0.3588890797
PubMed_21979375_A2Down-0.4534301995
GSE35957Up0.0695623614
GSE36640Up0.0857225686
GSE54402Up0.0103916065
GSE9593Up0.0495934800
GSE43922Up0.0588566389
GSE24585Up0.7596695263
GSE37065Down-0.0474093419
GSE28863_A1Down-0.0351718521
GSE28863_A2Down-0.2322558360
GSE28863_A3Up0.1465400165
GSE28863_A4Down-0.0248961412
GSE48662Up0.2990564442

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.