HCSGD entry for LETM1
1. General information
| Official gene symbol | LETM1 |
|---|---|
| Entrez ID | 3954 |
| Gene full name | leucine zipper-EF-hand containing transmembrane protein 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005739 | Mitochondrion | IDA ISS | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IDA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0042407 | Cristae formation | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3926470613 | 0.4508322138 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0065174791 |
| GSE13712_SHEAR | Up | 0.0232938670 |
| GSE13712_STATIC | Up | 0.1815681552 |
| GSE19018 | Down | -1.1088455522 |
| GSE19899_A1 | Up | 0.1199774509 |
| GSE19899_A2 | Up | 0.3067913636 |
| PubMed_21979375_A1 | Up | 0.3009490662 |
| PubMed_21979375_A2 | Up | 0.3927613505 |
| GSE35957 | Up | 0.0042835561 |
| GSE36640 | Down | -0.1344252277 |
| GSE54402 | Up | 0.1620959149 |
| GSE9593 | Down | -0.3619417653 |
| GSE43922 | Up | 0.1590489157 |
| GSE24585 | Down | -0.3413440425 |
| GSE37065 | Down | -0.2743528275 |
| GSE28863_A1 | Up | 0.3127130070 |
| GSE28863_A2 | Up | 0.2776146660 |
| GSE28863_A3 | Up | 0.1164469729 |
| GSE28863_A4 | Down | -0.0754248152 |
| GSE48662 | Up | 0.1016311444 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016307 | Proteomics | Functional MTI (Weak) | 21512034 |
| hsa-miR-1 | MIMAT0000416 | MIRT023539 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028844 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037046 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041761 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043486 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
