HCSGD entry for LAMC2
1. General information
| Official gene symbol | LAMC2 |
|---|---|
| Entrez ID | 3918 |
| Gene full name | laminin, gamma 2 |
| Other gene symbols | B2T BM600 CSF EBR2 EBR2A LAMB2T LAMNB2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005607 | Laminin-2 complex | IEA | cellular_component |
| GO:0005610 | Laminin-5 complex | IEA | cellular_component |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005938 | Cell cortex | IEA | cellular_component |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0008201 | Heparin binding | IEA | molecular_function |
| GO:0008544 | Epidermis development | TAS | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0030198 | Extracellular matrix organization | TAS | biological_process |
| GO:0031581 | Hemidesmosome assembly | TAS | biological_process |
| GO:0034329 | Cell junction assembly | TAS | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0006460469 | 0.9944142700 | 0.0740517391 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2517882320 |
| GSE13712_SHEAR | Up | 1.7020412278 |
| GSE13712_STATIC | Up | 0.8315692743 |
| GSE19018 | Up | 0.1490199567 |
| GSE19899_A1 | Up | 0.3196006568 |
| GSE19899_A2 | Up | 0.8499318670 |
| PubMed_21979375_A1 | Up | 1.4604458695 |
| PubMed_21979375_A2 | Up | 1.4516285148 |
| GSE35957 | Up | 0.5552071846 |
| GSE36640 | Up | 0.4509511269 |
| GSE54402 | Up | 1.6665169350 |
| GSE9593 | Up | 0.2211474179 |
| GSE43922 | Up | 1.5619827011 |
| GSE24585 | Up | 0.3245729167 |
| GSE37065 | Up | 0.4922676216 |
| GSE28863_A1 | Down | -0.2007359542 |
| GSE28863_A2 | Up | 0.2198575706 |
| GSE28863_A3 | Up | 0.0028538469 |
| GSE28863_A4 | Up | 0.1249272171 |
| GSE48662 | Down | -0.0825526962 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-199b-5p | MIMAT0000263 | MIRT002944 | Luciferase reporter assay | Functional MTI | 15131085 |
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019261 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025668 | Microarray | Functional MTI (Weak) | 19073608 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-199b-5p | MIMAT0000263 | 1 | hsa-miR-199b-5p | 15131085 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
