HCSGD entry for RHOG
1. General information
| Official gene symbol | RHOG |
|---|---|
| Entrez ID | 391 |
| Gene full name | ras homolog family member G |
| Other gene symbols | ARHG |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003924 | GTPase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006184 | GTP catabolic process | IDA TAS | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | TAS | biological_process |
| GO:0007266 | Rho protein signal transduction | IDA | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0008152 | Metabolic process | IDA TAS | biological_process |
| GO:0008284 | Positive regulation of cell proliferation | TAS | biological_process |
| GO:0016601 | Rac protein signal transduction | IDA | biological_process |
| GO:0030036 | Actin cytoskeleton organization | IDA | biological_process |
| GO:0030168 | Platelet activation | TAS | biological_process |
| GO:0032863 | Activation of Rac GTPase activity | IMP | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0051056 | Regulation of small GTPase mediated signal transduction | TAS | biological_process |
| GO:0060326 | Cell chemotaxis | IMP | biological_process |
| GO:0090004 | Positive regulation of establishment of protein localization to plasma membrane | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0155665134 | 0.9656010676 | 0.3095741692 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5380562747 |
| GSE13712_SHEAR | Up | 0.1294868359 |
| GSE13712_STATIC | Up | 0.0888665283 |
| GSE19018 | Up | 0.0094893616 |
| GSE19899_A1 | Up | 0.2402970058 |
| GSE19899_A2 | Up | 1.2206799777 |
| PubMed_21979375_A1 | Up | 2.1310746851 |
| PubMed_21979375_A2 | Up | 1.3251810695 |
| GSE35957 | Down | -0.6257380558 |
| GSE36640 | Up | 0.3532981970 |
| GSE54402 | Up | 0.5722043585 |
| GSE9593 | Up | 0.1789219940 |
| GSE43922 | Up | 0.1735766538 |
| GSE24585 | Up | 0.0644756669 |
| GSE37065 | Down | -0.0394303929 |
| GSE28863_A1 | Up | 0.0190707147 |
| GSE28863_A2 | Down | -0.0308175439 |
| GSE28863_A3 | Down | -0.1654470997 |
| GSE28863_A4 | Down | -0.0434982359 |
| GSE48662 | Up | 0.1587579614 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT001598 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT002922 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
