HCSGD entry for ACAT2
1. General information
| Official gene symbol | ACAT2 |
|---|---|
| Entrez ID | 39 |
| Gene full name | acetyl-CoA acetyltransferase 2 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003985 | Acetyl-CoA C-acetyltransferase activity | IDA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0006629 | Lipid metabolic process | IC | biological_process |
| GO:0016747 | Transferase activity, transferring acyl groups other than amino-acyl groups | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9679329623 | 0.0050843509 | 0.9999902473 | 0.1456775000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4787757125 |
| GSE13712_SHEAR | Up | 0.0211902036 |
| GSE13712_STATIC | Down | -0.3882842589 |
| GSE19018 | Down | -0.4245689847 |
| GSE19899_A1 | Down | -0.6649791857 |
| GSE19899_A2 | Down | -0.4972660491 |
| PubMed_21979375_A1 | Down | -1.5064747587 |
| PubMed_21979375_A2 | Down | -1.3981342130 |
| GSE35957 | Down | -0.3406550838 |
| GSE36640 | Down | -0.1798830618 |
| GSE54402 | Down | -0.6512182803 |
| GSE9593 | Down | -0.4372623835 |
| GSE43922 | Down | -0.7698097294 |
| GSE24585 | Down | -0.0404706203 |
| GSE37065 | Up | 0.4405123631 |
| GSE28863_A1 | Down | -0.3474758478 |
| GSE28863_A2 | Up | 0.0321385734 |
| GSE28863_A3 | Down | -0.2275211223 |
| GSE28863_A4 | Down | -0.1219277160 |
| GSE48662 | Down | -0.7665976128 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| S-Hydroxycysteine | DB01915 | EXPT01035 | DB03398 |
| Coenzyme A | DB01992 | EXPT00991 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022395 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049046 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
