HCSGD entry for MAP3K15
1. General information
| Official gene symbol | MAP3K15 |
|---|---|
| Entrez ID | 389840 |
| Gene full name | mitogen-activated protein kinase kinase kinase 15 |
| Other gene symbols | ASK3 bA723P2.3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000165 | MAPK cascade | IBA | biological_process |
| GO:0000186 | Activation of MAPKK activity | IBA | biological_process |
| GO:0004674 | Protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0004709 | MAP kinase kinase kinase activity | IBA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IBA | cellular_component |
| GO:0007165 | Signal transduction | IBA | biological_process |
| GO:0023014 | Signal transduction by phosphorylation | IBA | biological_process |
| GO:0035556 | Intracellular signal transduction | IBA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9505951104 | 0.5887234869 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | - | - |
| GSE13712_SHEAR | - | - |
| GSE13712_STATIC | - | - |
| GSE19018 | - | - |
| GSE19899_A1 | - | - |
| GSE19899_A2 | - | - |
| PubMed_21979375_A1 | - | - |
| PubMed_21979375_A2 | - | - |
| GSE35957 | - | - |
| GSE36640 | - | - |
| GSE54402 | - | - |
| GSE9593 | - | - |
| GSE43922 | Up | 0.0132977262 |
| GSE24585 | Down | -0.5403426548 |
| GSE37065 | Up | 0.0576328258 |
| GSE28863_A1 | Down | -0.0832754983 |
| GSE28863_A2 | Down | -0.0513923776 |
| GSE28863_A3 | Up | 0.0431761189 |
| GSE28863_A4 | Up | 0.0970747098 |
| GSE48662 | Down | -0.0292530566 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
