HCSGD entry for LAMTOR4
1. General information
| Official gene symbol | LAMTOR4 |
|---|---|
| Entrez ID | 389541 |
| Gene full name | late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 |
| Other gene symbols | C7orf59 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005085 | Guanyl-nucleotide exchange factor activity | IDA | molecular_function |
| GO:0005764 | Lysosome | IDA | cellular_component |
| GO:0008361 | Regulation of cell size | IMP | biological_process |
| GO:0032008 | Positive regulation of TOR signaling | IMP | biological_process |
| GO:0032947 | Protein complex scaffold | IDA | molecular_function |
| GO:0043087 | Regulation of GTPase activity | IDA | biological_process |
| GO:0061462 | Protein localization to lysosome | IMP | biological_process |
| GO:0071230 | Cellular response to amino acid stimulus | IMP | biological_process |
| GO:0071986 | Ragulator complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9032063106 | 0.1461370427 | 0.9999902473 | 0.7381449050 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2467473879 |
| GSE13712_SHEAR | Down | -0.3289383291 |
| GSE13712_STATIC | Down | -0.1387097084 |
| GSE19018 | Down | -0.1724332834 |
| GSE19899_A1 | Down | -0.3020226070 |
| GSE19899_A2 | Down | -0.0772526601 |
| PubMed_21979375_A1 | Up | 0.4308521725 |
| PubMed_21979375_A2 | Up | 0.0672749676 |
| GSE35957 | Down | -0.1356145069 |
| GSE36640 | Down | -0.0297992033 |
| GSE54402 | Up | 0.0892710741 |
| GSE9593 | Up | 0.1106160892 |
| GSE43922 | Down | -0.0821333427 |
| GSE24585 | Down | -0.3616389988 |
| GSE37065 | Down | -0.1095820690 |
| GSE28863_A1 | Down | -0.1392872813 |
| GSE28863_A2 | Down | -0.0874320478 |
| GSE28863_A3 | Up | 0.0841951101 |
| GSE28863_A4 | Down | -0.0021039122 |
| GSE48662 | Down | -0.2775810392 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT032024 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-766-3p | MIMAT0003888 | MIRT039053 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-424-5p | MIMAT0001341 | MIRT042451 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043434 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
