HCSGD entry for KRT1
1. General information
| Official gene symbol | KRT1 |
|---|---|
| Entrez ID | 3848 |
| Gene full name | keratin 1 |
| Other gene symbols | CK1 EHK EHK1 EPPK K1 KRT1A NEPPK |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001867 | Complement activation, lectin pathway | IPI | biological_process |
| GO:0004872 | Receptor activity | NAS | molecular_function |
| GO:0005198 | Structural molecule activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005856 | Cytoskeleton | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006979 | Response to oxidative stress | NAS | biological_process |
| GO:0016020 | Membrane | IDA | cellular_component |
| GO:0030246 | Carbohydrate binding | IPI | molecular_function |
| GO:0042730 | Fibrinolysis | NAS | biological_process |
| GO:0045095 | Keratin filament | IEA | cellular_component |
| GO:0045765 | Regulation of angiogenesis | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8179292542 | 0.8253254740 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0257335893 |
| GSE13712_SHEAR | Down | -0.0344961287 |
| GSE13712_STATIC | Up | 0.1290562093 |
| GSE19018 | Down | -0.0169308413 |
| GSE19899_A1 | Down | -0.0539683565 |
| GSE19899_A2 | Down | -0.1433588067 |
| PubMed_21979375_A1 | Up | 0.0571142120 |
| PubMed_21979375_A2 | Down | -0.1109974573 |
| GSE35957 | Down | -0.0574488826 |
| GSE36640 | Up | 0.1098675231 |
| GSE54402 | Down | -0.0726799364 |
| GSE9593 | Up | 0.0433150008 |
| GSE43922 | Up | 0.0169711480 |
| GSE24585 | Up | 0.0050581958 |
| GSE37065 | Up | 0.0453729856 |
| GSE28863_A1 | Up | 0.0579166240 |
| GSE28863_A2 | Up | 0.0882527359 |
| GSE28863_A3 | Up | 0.2116787056 |
| GSE28863_A4 | Up | 0.0579514359 |
| GSE48662 | Down | -0.1029019281 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 22686306 | These data were confirmed by a fall in mRNA expression levels of keratin 1 and transglutaminase 1 within the passages |
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