HCSGD entry for KPNA4
1. General information
| Official gene symbol | KPNA4 |
|---|---|
| Entrez ID | 3840 |
| Gene full name | karyopherin alpha 4 (importin alpha 3) |
| Other gene symbols | IPOA3 QIP1 SRP3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006607 | NLS-bearing protein import into nucleus | TAS | biological_process |
| GO:0008565 | Protein transporter activity | IEA | molecular_function |
| GO:0019221 | Cytokine-mediated signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0430530451 | 0.9536968694 | 0.4619646148 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1661419072 |
| GSE13712_SHEAR | Up | 0.5172764152 |
| GSE13712_STATIC | Up | 0.3075540114 |
| GSE19018 | Down | -0.2101664870 |
| GSE19899_A1 | Up | 0.6880523384 |
| GSE19899_A2 | Up | 0.5431824049 |
| PubMed_21979375_A1 | Up | 0.3864724696 |
| PubMed_21979375_A2 | Up | 0.4607825581 |
| GSE35957 | Up | 0.2465433557 |
| GSE36640 | Up | 0.0673648881 |
| GSE54402 | Up | 0.2315304558 |
| GSE9593 | Up | 0.1211610427 |
| GSE43922 | Up | 0.3842190117 |
| GSE24585 | Down | -0.2681142666 |
| GSE37065 | Up | 0.1022130719 |
| GSE28863_A1 | Down | -0.0062226522 |
| GSE28863_A2 | Up | 0.3872213438 |
| GSE28863_A3 | Down | -0.2889125072 |
| GSE28863_A4 | Down | -0.1370205535 |
| GSE48662 | Down | -0.0165380711 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019944 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028598 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
