HCSGD entry for KIF22
1. General information
| Official gene symbol | KIF22 |
|---|---|
| Entrez ID | 3835 |
| Gene full name | kinesin family member 22 |
| Other gene symbols | A-328A3.2 KID KNSL4 OBP OBP-1 OBP-2 SEMDJL2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000776 | Kinetochore | TAS | cellular_component |
| GO:0000785 | Chromatin | IEA | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003777 | Microtubule motor activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005819 | Spindle | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005871 | Kinesin complex | IEA | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0005925 | Focal adhesion | IDA | cellular_component |
| GO:0006281 | DNA repair | IEA | biological_process |
| GO:0007018 | Microtubule-based movement | IEA TAS | biological_process |
| GO:0007067 | Mitosis | TAS | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0008017 | Microtubule binding | IEA | molecular_function |
| GO:0019886 | Antigen processing and presentation of exogenous peptide antigen via MHC class II | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9494509441 | 0.0044139508 | 0.9999902473 | 0.1352498254 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0368500688 |
| GSE13712_SHEAR | Down | -0.2651077966 |
| GSE13712_STATIC | Down | -0.9768429631 |
| GSE19018 | Up | 0.0731755158 |
| GSE19899_A1 | Down | -0.1780942030 |
| GSE19899_A2 | Down | -1.2464277803 |
| PubMed_21979375_A1 | Down | -0.7046832896 |
| PubMed_21979375_A2 | Down | -1.2098125920 |
| GSE35957 | Down | -1.4737713901 |
| GSE36640 | Down | -1.4837509572 |
| GSE54402 | Down | -0.1352121816 |
| GSE9593 | Down | -0.5587607070 |
| GSE43922 | Down | -0.6487913347 |
| GSE24585 | Down | -0.0018138307 |
| GSE37065 | Down | -0.2042771143 |
| GSE28863_A1 | Down | -0.2180748771 |
| GSE28863_A2 | Up | 0.2575494966 |
| GSE28863_A3 | Up | 0.3436810218 |
| GSE28863_A4 | Up | 0.2450758565 |
| GSE48662 | Down | -1.0890292548 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-146a-5p | MIMAT0000449 | MIRT005706 | Western blot | Non-Functional MTI | 19944095 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016267 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020596 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-25-5p | MIMAT0004498 | MIRT038956 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045570 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23a-3p | MIMAT0000078 | MIRT050414 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-146a-5p | MIMAT0000449 | NA | hsa-miR-146a | 19944095 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
