HCSGD entry for KLC1
1. General information
| Official gene symbol | KLC1 |
|---|---|
| Entrez ID | 3831 |
| Gene full name | kinesin light chain 1 |
| Other gene symbols | KLC KNS2 KNS2A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003774 | Motor activity | TAS | molecular_function |
| GO:0003777 | Microtubule motor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | ISS TAS | cellular_component |
| GO:0005871 | Kinesin complex | IEA ISS | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0006886 | Intracellular protein transport | IEA | biological_process |
| GO:0007018 | Microtubule-based movement | TAS | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0008088 | Axon cargo transport | IEA | biological_process |
| GO:0008152 | Metabolic process | TAS | biological_process |
| GO:0015631 | Tubulin binding | IEA | molecular_function |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0019886 | Antigen processing and presentation of exogenous peptide antigen via MHC class II | TAS | biological_process |
| GO:0030424 | Axon | IEA | cellular_component |
| GO:0031410 | Cytoplasmic vesicle | IEA | cellular_component |
| GO:0031982 | Vesicle | IEA | cellular_component |
| GO:0035253 | Ciliary rootlet | IEA | cellular_component |
| GO:0035418 | Protein localization to synapse | IEA | biological_process |
| GO:0035617 | Stress granule disassembly | ISS | biological_process |
| GO:0043025 | Neuronal cell body | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0836573496 | 0.9529820676 | 0.6087766381 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0306121407 |
| GSE13712_SHEAR | Up | 0.0704660798 |
| GSE13712_STATIC | Up | 0.3026161311 |
| GSE19018 | Up | 0.1348162492 |
| GSE19899_A1 | Down | -0.2511224470 |
| GSE19899_A2 | Up | 0.7242522684 |
| PubMed_21979375_A1 | Up | 0.2464954922 |
| PubMed_21979375_A2 | Up | 0.1270257809 |
| GSE35957 | Up | 0.2541539780 |
| GSE36640 | Up | 0.8597583587 |
| GSE54402 | Up | 0.3774456527 |
| GSE9593 | Up | 0.3051775368 |
| GSE43922 | Down | -0.0091031772 |
| GSE24585 | Up | 0.3030086702 |
| GSE37065 | Up | 0.0864528628 |
| GSE28863_A1 | Down | -0.1281330472 |
| GSE28863_A2 | Up | 0.1362335035 |
| GSE28863_A3 | Down | -0.2065132427 |
| GSE28863_A4 | Up | 0.1227653321 |
| GSE48662 | Up | 0.0645976500 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-197-3p | MIMAT0000227 | MIRT004189 | Microarray | Functional MTI (Weak) | 16822819 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025439 | Proteomics | Functional MTI (Weak) | 21566225 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
