HCSGD entry for KIF5A
1. General information
| Official gene symbol | KIF5A |
|---|---|
| Entrez ID | 3798 |
| Gene full name | kinesin family member 5A |
| Other gene symbols | D12S1889 MY050 NKHC SPG10 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003774 | Motor activity | TAS | molecular_function |
| GO:0003777 | Microtubule motor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005871 | Kinesin complex | IEA | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0007018 | Microtubule-based movement | IEA TAS | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0008017 | Microtubule binding | IEA | molecular_function |
| GO:0008152 | Metabolic process | TAS | biological_process |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0019886 | Antigen processing and presentation of exogenous peptide antigen via MHC class II | TAS | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1804015311 | 0.9073697466 | 0.8323582633 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0456636767 |
| GSE13712_SHEAR | Up | 0.0145313084 |
| GSE13712_STATIC | Up | 0.0283887496 |
| GSE19018 | Up | 0.0883697800 |
| GSE19899_A1 | Up | 0.1807984479 |
| GSE19899_A2 | Up | 0.0885492124 |
| PubMed_21979375_A1 | Up | 0.2757697111 |
| PubMed_21979375_A2 | Up | 0.1638685870 |
| GSE35957 | Up | 0.0232439567 |
| GSE36640 | Up | 1.6209658378 |
| GSE54402 | Up | 0.0541991127 |
| GSE9593 | Down | -0.0193676867 |
| GSE43922 | Up | 0.0190952178 |
| GSE24585 | Up | 0.1706101570 |
| GSE37065 | Down | -0.1107177167 |
| GSE28863_A1 | Down | -0.1160902195 |
| GSE28863_A2 | Up | 0.9770096431 |
| GSE28863_A3 | Down | -0.1947865108 |
| GSE28863_A4 | Down | -0.1169755917 |
| GSE48662 | Up | 0.0186315595 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027231 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT032072 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
