HCSGD entry for KHK
1. General information
| Official gene symbol | KHK |
|---|---|
| Entrez ID | 3795 |
| Gene full name | ketohexokinase (fructokinase) |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004454 | Ketohexokinase activity | EXP IDA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0006001 | Fructose catabolic process | TAS | biological_process |
| GO:0008152 | Metabolic process | IDA | biological_process |
| GO:0016310 | Phosphorylation | IDA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046835 | Carbohydrate phosphorylation | EXP IDA TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8457054253 | 0.4306264884 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0569099863 |
| GSE13712_SHEAR | Down | -0.1110682386 |
| GSE13712_STATIC | Down | -0.3558824856 |
| GSE19018 | Down | -0.0024815313 |
| GSE19899_A1 | Down | -0.0081932385 |
| GSE19899_A2 | Down | -0.0370789399 |
| PubMed_21979375_A1 | Up | 0.1245832046 |
| PubMed_21979375_A2 | Down | -0.0849094499 |
| GSE35957 | Down | -0.0418493319 |
| GSE36640 | Down | -0.1469095588 |
| GSE54402 | Down | -0.0796820272 |
| GSE9593 | Up | 0.2265815994 |
| GSE43922 | Up | 0.0233394672 |
| GSE24585 | Down | -0.6502393170 |
| GSE37065 | Down | -0.0446439693 |
| GSE28863_A1 | Down | -0.0149243673 |
| GSE28863_A2 | Up | 0.2574394980 |
| GSE28863_A3 | Up | 0.2254820303 |
| GSE28863_A4 | Up | 0.1584843681 |
| GSE48662 | Up | 0.0867095033 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019807 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029406 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
