HCSGD entry for KCNN3

1. General information

Official gene symbolKCNN3
Entrez ID3782
Gene full namepotassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
Other gene symbolsKCa2.3 SK3 SKCA3 hSK3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005516Calmodulin bindingIEAmolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0007268Synaptic transmissionTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016286Small conductance calcium-activated potassium channel activityIEAmolecular_function
GO:0030175FilopodiumIEAcellular_component
GO:0031594Neuromuscular junctionIEAcellular_component
GO:0043005Neuron projectionIEAcellular_component
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0046982Protein heterodimerization activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.56770123100.59532600970.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2568010207
GSE13712_SHEARDown-1.3676879829
GSE13712_STATICDown-0.1631988807
GSE19018Up0.0712408566
GSE19899_A1Up0.0424244357
GSE19899_A2Up0.0895689153
PubMed_21979375_A1Up0.0879265951
PubMed_21979375_A2Down-0.0104026175
GSE35957Up0.0567909338
GSE36640Up0.0008008080
GSE54402Up0.0189756449
GSE9593Up0.0249168314
GSE43922Up0.1080266921
GSE24585Up0.0363833363
GSE37065Up0.0665808693
GSE28863_A1Down-0.0870769951
GSE28863_A2Down-0.1279780248
GSE28863_A3Up0.3409621077
GSE28863_A4Up0.1207500110
GSE48662Down-0.0267931692

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

MiconazoleDB01110 APRD01115

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.