HCSGD entry for ARF4
1. General information
| Official gene symbol | ARF4 |
|---|---|
| Entrez ID | 378 |
| Gene full name | ADP-ribosylation factor 4 |
| Other gene symbols | ARF2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0007173 | Epidermal growth factor receptor signaling pathway | IEA | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0007420 | Brain development | IEA | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0016192 | Vesicle-mediated transport | IEA | biological_process |
| GO:0048678 | Response to axon injury | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3882174841 | 0.8088286729 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0963549308 |
| GSE13712_SHEAR | Up | 0.2943636782 |
| GSE13712_STATIC | Up | 0.1254548897 |
| GSE19018 | Down | -0.0606720813 |
| GSE19899_A1 | Up | 0.1563820652 |
| GSE19899_A2 | Up | 0.0255100318 |
| PubMed_21979375_A1 | Up | 0.1613344940 |
| PubMed_21979375_A2 | Up | 0.0019079753 |
| GSE35957 | Up | 0.1222233502 |
| GSE36640 | Up | 0.4647021927 |
| GSE54402 | Up | 0.1077204754 |
| GSE9593 | Up | 0.1512809061 |
| GSE43922 | Up | 0.0290569361 |
| GSE24585 | Up | 0.3828765496 |
| GSE37065 | Down | -0.0304731430 |
| GSE28863_A1 | Down | -0.0624394595 |
| GSE28863_A2 | Down | -0.0001811208 |
| GSE28863_A3 | Down | -0.3702212376 |
| GSE28863_A4 | Down | -0.2579606827 |
| GSE48662 | Down | -0.3551727008 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Guanosine-5'-Diphosphate | DB04315 | EXPT01573 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT002823 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-1 | MIMAT0000416 | MIRT002823 | pSILAC//Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT004061 | Microarray//Microarray;Other | Functional MTI (Weak) | 19073608 |
| hsa-miR-361-5p | MIMAT0000703 | MIRT020084 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-142-3p | MIMAT0000434 | MIRT021610 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | NA | hsa-miR-1 | 15685193 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 23634235 | Amongst the genes were IRAK3, SelS, HSPA5, HERPUD1, DNAJB9, SEPR1, C18orf55, ARF4, RINT1, NXT1, CADPS2, COG6, and GLRX5 |
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