HCSGD entry for KCNK3

1. General information

Official gene symbolKCNK3
Entrez ID3777
Gene full namepotassium channel, subfamily K, member 3
Other gene symbolsK2p3.1 OAT1 TASK TASK-1 TBAK1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005252Open rectifier potassium channel activityIEAmolecular_function
GO:0005267Potassium channel activityTASmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006813Potassium ion transportTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007420Brain developmentIEAbiological_process
GO:0008022Protein C-terminus bindingIEAmolecular_function
GO:0022841Potassium ion leak channel activityIDAmolecular_function
GO:0042493Response to drugIEAbiological_process
GO:0042803Protein homodimerization activityIEAmolecular_function
GO:0046982Protein heterodimerization activityIEAmolecular_function
GO:0051481Negative regulation of cytosolic calcium ion concentrationIEAbiological_process
GO:0071294Cellular response to zinc ionIEAbiological_process
GO:0071456Cellular response to hypoxiaIEAbiological_process
GO:0090102Cochlea developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.26646309790.85972171650.96243179331.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0982321488
GSE13712_SHEARDown-0.4334708657
GSE13712_STATICUp0.1623151748
GSE19018Up0.1257002528
GSE19899_A1Up0.0206775961
GSE19899_A2Up0.1246423976
PubMed_21979375_A1Up0.3675560252
PubMed_21979375_A2Down-0.0835978361
GSE35957Up0.2126838343
GSE36640Up0.0341633832
GSE54402Up0.4737673660
GSE9593Down-1.0814403282
GSE43922Up0.0964023174
GSE24585Up0.0157572092
GSE37065Up0.1790059288
GSE28863_A1Up0.0236267690
GSE28863_A2Up0.1929745100
GSE28863_A3Up0.0512915732
GSE28863_A4Up0.1527834200
GSE48662Up0.0581367381

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

DoxapramDB00561 APRD00935

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.