HCSGD entry for KCNJ10

1. General information

Official gene symbolKCNJ10
Entrez ID3766
Gene full namepotassium inwardly-rectifying channel, subfamily J, member 10
Other gene symbolsBIRK-10 KCNJ13-PEN KIR1.2 KIR4.1 SESAME
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005102Receptor bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0005902MicrovillusIEAcellular_component
GO:0006813Potassium ion transportTASbiological_process
GO:0006954Inflammatory responseIEAbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007601Visual perceptionIEAbiological_process
GO:0007628Adult walking behaviorIEAbiological_process
GO:0009637Response to blue lightIEAbiological_process
GO:0010107Potassium ion importIEAbiological_process
GO:0015272ATP-activated inward rectifier potassium channel activityTASmolecular_function
GO:0016010Dystrophin-associated glycoprotein complexIEAcellular_component
GO:0016323Basolateral plasma membraneIEAcellular_component
GO:0016324Apical plasma membraneIEAcellular_component
GO:0021554Optic nerve developmentIEAbiological_process
GO:0022010Central nervous system myelinationIEAbiological_process
GO:0042802Identical protein bindingIEAmolecular_function
GO:0048169Regulation of long-term neuronal synaptic plasticityIEAbiological_process
GO:0051289Protein homotetramerizationIEAbiological_process
GO:0051384Response to glucocorticoidIEAbiological_process
GO:0051385Response to mineralocorticoidIEAbiological_process
GO:0051930Regulation of sensory perception of painIEAbiological_process
GO:0051935L-glutamate uptake involved in synaptic transmissionIEAbiological_process
GO:0055075Potassium ion homeostasisIEAbiological_process
GO:0060075Regulation of resting membrane potentialIEAbiological_process
GO:0060081Membrane hyperpolarizationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.74796727330.67926013070.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0816255911
GSE13712_SHEARDown-0.1496241058
GSE13712_STATICDown-0.0282647585
GSE19018Down-0.1071425849
GSE19899_A1Up0.0110124042
GSE19899_A2Up0.0757786761
PubMed_21979375_A1Up0.1543319200
PubMed_21979375_A2Down-0.0491834621
GSE35957Up0.0833314730
GSE36640Up0.0048831214
GSE54402Down-0.1047769787
GSE9593Up0.0370814352
GSE43922Up0.0436730776
GSE24585Up0.2294620163
GSE37065Up0.1186015320
GSE28863_A1Down-0.1649157952
GSE28863_A2Down-0.1637237492
GSE28863_A3Up0.1811174131
GSE28863_A4Up0.2164793287
GSE48662Down-0.0843708573

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.