HCSGD entry for KCNJ8

1. General information

Official gene symbolKCNJ8
Entrez ID3764
Gene full namepotassium inwardly-rectifying channel, subfamily J, member 8
Other gene symbolsKIR6.1 uKATP-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001822Kidney developmentIEAbiological_process
GO:0005242Inward rectifier potassium channel activityTASmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005739MitochondrionIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006813Potassium ion transportTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007507Heart developmentIEAbiological_process
GO:0008076Voltage-gated potassium channel complexTAScellular_component
GO:0008282ATP-sensitive potassium channel complexIEAcellular_component
GO:0009268Response to pHIEAbiological_process
GO:0010107Potassium ion importIEAbiological_process
GO:0015272ATP-activated inward rectifier potassium channel activityIEAmolecular_function
GO:0017098Sulfonylurea receptor bindingIEAmolecular_function
GO:0030016MyofibrilIEAcellular_component
GO:0032496Response to lipopolysaccharideIEAbiological_process
GO:0042311VasodilationIEAbiological_process
GO:0042383SarcolemmaIEAcellular_component
GO:0043330Response to exogenous dsRNAIEAbiological_process
GO:0051607Defense response to virusIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.99374945860.00022149230.99999024730.0259106667

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1024613802
GSE13712_SHEARDown-0.0083324348
GSE13712_STATICDown-0.0904571807
GSE19018Up0.3115945513
GSE19899_A1Down-0.2975293103
GSE19899_A2Down-2.6558520228
PubMed_21979375_A1Down-4.5010204009
PubMed_21979375_A2Down-2.8514660000
GSE35957Up0.0061858576
GSE36640Down-3.6082987717
GSE54402Down-2.3899134233
GSE9593Down-1.0180876262
GSE43922Down-0.8229594407
GSE24585Down-0.1024328170
GSE37065Down-0.3562239494
GSE28863_A1Down-0.1816642090
GSE28863_A2Up0.1828670598
GSE28863_A3Down-0.3366446512
GSE28863_A4Down-0.5097702371
GSE48662Down-0.6584653524

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

PhenforminDB00914 APRD00511
LevosimendanDB00922 APRD01296
GliquidoneDB01251 -
GlisoxepideDB01289 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.